Generic levothyroxine initiation and substitution among Medicare and Medicaid...
AbstractPurposeGeneric levothyroxine has been approved and available since 2004 but its substitution remains controversial. Therefore, the objective was to examine patterns of and identify factors...
View ArticleSeismic performance evaluation of large-span offshore cable-stayed bridges...
AbstractThis paper presents a novel and precise seismic performance evaluation method for large-span offshore cable-stayed (LSOCS) bridge by considering the strain rate effect of RC materials and the...
View ArticleNovel Brønsted–Lewis acidic di-cationic ionic liquid for efficient conversion...
AbstractA series of Brønsted–Lewis acidic di-cationic ionic liquids (BLAILs) were synthesized and the catalytic properties of glucose conversion to 5-hydroxymethylfurfural (5-HMF) were investigated....
View ArticleWhole-genome sequencing of Chinese centenarians reveals important genetic...
AbstractBackgroundGenetic research on longevity has provided important insights into the mechanism of aging and aging-related diseases. Pinpointing import genetic variants associated with aging could...
View ArticleSWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase...
AbstractWe describe here a CRISPR simultaneous and wide-editing induced by a single system (SWISS), in which RNA aptamers engineered in crRNA scaffold recruit their cognate binding proteins fused with...
View ArticlePossible influences of a La Niña event on a continuous tropical cyclone...
AbstractFour tropical cyclones (TCs) formed over the western North Pacific (WNP) basin and continuously made landfall on the coastal areas of the eastern China mainland during July–August in 2018 and...
View ArticleModeling of instantaneous cutting force for large pitch screw with vibration...
AbstractThe instantaneous cutting force is the key indicator to impact surface quality of the workpiece and processing performance. In this article, from the point of view of machine tool processing...
View ArticleInvestigation on precision warm hydroforming with independent circumferential...
AbstractHigh-performance aluminum alloy is light, has high strength, but is very difficult to be formed. In the forming process of aluminum alloy parts with special-shaped bottom, there are defects...
View ArticleHighly efficient generation of sheep with a defined FecB B mutation via...
AbstractBase editing has the potential to improve important economic traits in agriculture and can precisely convert single nucleotides in DNA or RNA sequences into minimal double-strand DNA breaks...
View ArticleSulforaphane alter the microbiota and mitigate colitis severity on mice...
AbstractSulforaphane (SFN) is a kind of natural isothiocyanate, which exists in cruciferous plants. Only few studies were about the anti-inflammatory effects of sulforaphane in ulcerative colitis. In...
View ArticleDiversity-guided Lamarckian random drift particle swarm optimization for...
AbstractBackgroundProtein-ligand docking has emerged as a particularly important tool in drug design and development, and flexible ligand docking is a widely used method for docking simulations. Many...
View ArticleTemperature-Dependent Crystallization of Ga 2 O 3 for Ultraviolet Photodetectors
AbstractAs an n-type oxide semiconductor, Ga2O3 shows great promise in solar-blind ultraviolet (UV) photodetectors due to its adequate band gap, high absorption coefficient, high thermal and chemical...
View ArticleThe MRTF-A/miR-155/SOX1 pathway mediates gastric cancer migration and invasion
AbstractBackgroundGastric cancer (GC) is the leading cause of death worldwide and is closely related to metastasis. MRTF-A is one of the most well-characterized genetic markers in cancer. However, the...
View ArticleConstruction of 6061-T6 aluminum alloy constitutive model based on hot...
AbstractDue to the high requirements of drawing equipment and process, it is relatively rare in the field of aluminum alloy sheet forming to introduce soft or sticky fluid medias as soft mold into the...
View ArticlePreoperative tumor biopsy results in more detected sentinel nodes than...
AbstractBackgroundSentinel lymph node biopsy (SLNB) plays a vital role in breast cancer surgery, and the identified number of sentinel nodes determines its accuracy for representing the status of the...
View ArticleUnsupervised video-to-video translation with preservation of frame...
AbstractTremendous advances have been achieved in image translation with the employment of generative adversarial networks (GANs). With respect to video-to-video translation, similar idea has been...
View ArticleComputational study on the performance improvement of axial-flow pump by...
AbstractIn order to investigate the influence of adjustable inlet guide vanes on the hydraulic performance of axial-flow pump and impeller, the axial-flow pump with different inlet guide vane...
View ArticleThe phantom of differential characteristics
AbstractFor differential cryptanalysis under the single-key model, the key schedules hardly need to be exploited in constructing the characteristics, which is based on the hypothesis of stochastic...
View ArticleClinical characteristics of 276 hospitalized patients with coronavirus...
AbstractBackgroundWe aimed to report the epidemiological and clinical characteristics of hospitalized patients with coronavirus disease-19 (COVID-19) in Zengdu District, Hubei Province,...
View ArticlePredictive value of prenatal ultrasound parameters for dichorionic growth...
AbstractBackgroundTwin growth discordance was demonstrated to be a risk factor for adverse perinatal outcomes, and prenatal ultrasonographic methods were utilized to predict twin growth discordance to...
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